{"id":1892,"date":"2023-10-02T17:19:28","date_gmt":"2023-10-02T11:49:28","guid":{"rendered":"https:\/\/narihealth.tanshcreative.com\/?page_id=1892"},"modified":"2025-12-03T07:57:15","modified_gmt":"2025-12-03T07:57:15","slug":"testimonials","status":"publish","type":"page","link":"https:\/\/polikistikover.net\/yeni\/testimonials\/","title":{"rendered":"Op. Dr. Burak Hac\u0131hanefio\u011flu"},"content":{"rendered":"
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Op. Dr. Burak HACIHANEF\u0130O\u011eLU<\/strong><\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu 1969 y\u0131l\u0131nda \u0130stanbul\u2019da do\u011fdu. 1986 y\u0131l\u0131nda girdi\u011fi Hacettepe \u00dcniversitesi T\u0131p Fak\u00fcltesinden 1993 y\u0131l\u0131nda mezun oldu. 1993-1999 y\u0131llar\u0131 aras\u0131nda \u0130stanbul \u00dcniversitesi Cerrahpa\u015fa T\u0131p Fak\u00fcltesi\u2019nde Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum ihtisas\u0131 yapt\u0131. Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum ihtisas\u0131 d\u00f6neminde \u2018\u2019Polikistik Ovaryum Sendromunda \u0130ns\u00fclin Direnci ve Renin-Angiotensin sistemi (RAS) aras\u0131ndaki ili\u015fkinin de\u011ferlendirilmesi\u2019\u2019 konulu tezini tamamlad\u0131. Polikistik over sendromu\u2019nda yumurtal\u0131k kaynakl\u0131 renin-angiotensin sisteminin ins\u00fclin direncinden ba\u011f\u0131ms\u0131z olarak etkin oldu\u011fu d\u00fcnyada ilk defa bu \u00e7al\u0131\u015fmada g\u00f6sterilmi\u015ftir.<\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum ihtisas\u0131n\u0131 bitirdikten sonra sonra 1999 y\u0131l\u0131nda halen Karolinska Enstit\u00fcs\u00fcnde \u00e7al\u0131\u015fan Profes\u00f6r Dr. Sven Eric Olsson ile birlikte \u0130sve\u00e7\u2019te Orebro \u00dcniversitesinde polikistik over sendromu\u2019nda yumurta geli\u015fimi ve yumurtlama konusunda \u00e7al\u0131\u015fmalarda bulundu.<\/p>\n\n\n\n

2000-2002 y\u0131llar\u0131 aras\u0131nda \u0130ngiltere, Londra\u2019da Newham \u00dcniversite hastanesinde \u00dcreme Endokrinolojisi b\u00f6l\u00fcm\u00fcnde ara\u015ft\u0131rma g\u00f6revlisi olarak Profes\u00f6r Dr. Ovrang Djahanbakhch ile birlikte  \u00e7al\u0131\u015ft\u0131. Bu d\u00f6nemde haz\u0131rlad\u0131\u011f\u0131 \u2018\u2019Investigation of apoptotic and cell cycle pathways in granulosa cells of women with polycystic ovary syndrome\u2019\u2019 ba\u015fl\u0131kl\u0131 projesinin tamamlanmas\u0131 i\u00e7in Queen Mary University of London, Barts and The London School of Medicine and Dentistry taraf\u0131ndan maddi destek ile \u00f6d\u00fcllendirildi. Ara\u015ft\u0131rma g\u00f6revlisi oldu\u011fu bu d\u00f6nemde Newham \u00dcniversite hastanesinde polikistik over sendromu klini\u011finde \u00e7al\u0131\u015ft\u0131.<\/p>\n\n\n\n

2000-2003 y\u0131llar\u0131 aras\u0131nda do\u011fu Londra\u2019n\u0131n farkl\u0131 mahallelerinde g\u00f6rev yapan pratisyen doktorlar\u0131n (GPs) polikistik over sendromu hakk\u0131nda bilgilerini artt\u0131rmak amac\u0131yla seminerler verdi. 2004 y\u0131l\u0131nda, Londra\u2019da The Royal Society of Medicine taraf\u0131ndan d\u00fczenlenen polikistik over sendromu toplant\u0131s\u0131nda Fertility and Sterility dergisinde yay\u0131nlanm\u0131\u015f olan \u201dPolycystic ovary syndrome nomenclature: chaos?\u201d ba\u015fl\u0131kl\u0131 editorial\u2019 \u0131n\u0131n sunumunu yapt\u0131.<\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu, 2008 y\u0131l\u0131ndan beri, \u0130stanbul, T\u00fcrkiye\u2019de kurucusu oldu\u011fu Polikistik Over Klini\u011finde<\/strong> \u00e7al\u0131\u015fmaktad\u0131r.<\/p>\n\n\n\n

2008-2013 y\u0131llar\u0131 aras\u0131nda, polikistik over sendromu olan kad\u0131nlar\u0131n sex hormone binding globulin (SHBG) geninde, exon 8 \u00fczerinde yap\u0131lan genetik analiz ile genetik farkl\u0131l\u0131klar\u0131 (polymorphism) ara\u015ft\u0131rd\u0131. SHBG geninde exon 8 de g\u00f6r\u00fclen genetik farkl\u0131l\u0131k (E326K single nucleotide polymorphism) d\u00fcnyada ilk defa bu \u00e7al\u0131\u015fmada g\u00f6sterilmi\u015ftir.<\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu T\u00fcrk\u00e7e ve \u0130ngilizce, bilimsel referanslar\u0131 temel alarak haz\u0131rlam\u0131\u015f oldu\u011fu polikistik over sendromu hakk\u0131ndaki websitelerini (www.polikistikover.net, www.polikistikover.org www.polycysticovary.net) yeni bilimsel geli\u015fmeler do\u011frultusunda d\u00fczenli olarak yenilemektedir.<\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu 2002 y\u0131l\u0131nda San Fransisco, California\u2019 da kurulan Androgen Excess and PCOS Society\u2019 nin 50 kurucu \u00fcyesinden biridir. The Endocrine Society, T\u00fcrk Jinekoloji ve Obstetrik Derne\u011fi ve T\u00fcrk Androloji Derne\u011finin \u00fcyesidir.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Dr. Burak Hac\u0131hanefio\u011flu\u2019nun bilimsel dergilerde yay\u0131nlanm\u0131\u015f (peer-reviewed) bilimsel \u00e7al\u0131\u015fmalar\u0131;<\/mark><\/strong><\/p>\n\n\n\n

Gynecol Endocrinol.<\/a><\/strong> 2013 Apr;29(4):361-4. Association of anthropometric, androgenic and insulin-related features with polymorphisms in exon 8 of SHBG gene in women with polyacystic ovary syndrome.<\/a> <\/strong><\/p>\n\n\n\n

Hac\u0131hanefio\u011flu B, Aybey B, Hakan \u00d6z\u00f6n Y, Berkil H, Kar\u015f\u0131da\u011f K.<\/p>\n\n\n\n

J Clin Endocrinol Metab. <\/strong>2008 Mar;93(3):881-7. Granulosa cell survival and proliferation are altered in polycystic ovary syndrome.<\/strong> <\/a><\/p>\n\n\n\n

Das M, Djahanbakhch O, Hacihanefioglu B, Saridogan E, Ikram M, Ghali L, Raveendran M, Storey A.<\/p>\n\n\n\n

CPD Clinical Biochemistry.<\/strong> 2003; 5(1):8-13. <\/strong><\/em>Pathogenesis and metabolic manifestations of polycystic ovary syndrome. <\/strong><\/p>\n\n\n\n

Burak Hacihanefioglu & Sudha Bulusu.<\/p>\n\n\n\n

Fertil Steril.<\/a><\/strong> 2002 Mar;77(3):526-8. Effect of hypertension therapy with the angiotensin-converting enzyme inhibitor lisinopril on hyperandrogenism in women with polycystic ovary syndrome.<\/a> <\/em><\/strong><\/p>\n\n\n\n

Hacihanefioglu B<\/a>, <\/a>Somunkiran A<\/a>, <\/a>Mahmutoglu I<\/a>, <\/a>Sercelik A<\/a>, <\/a>Toptani S<\/a>, <\/a>Kervancioglu E<\/a>.<\/p>\n\n\n\n

Fertil Steril.<\/strong> <\/a>2000 Jun;73(6):1261-2. Polycystic ovary syndrome nomenclature: chaos?<\/a><\/strong><\/p>\n\n\n\n

  Hacihanefioglu Burak.<\/p>\n\n\n\n

Fertil Steril. <\/a><\/strong>2000 Feb;73(2):261-5. Influence of insulin resistance on total renin level in normotensive women with polycystic ovary syndrome.<\/a> <\/em><\/strong><\/p>\n\n\n\n

Hacihanefioglu B, Seyisoglu  H<\/a>, Karsidag K<\/a>, Elter K<\/a>, Aksu F<\/a>, Yilmaz T<\/a>, Gurol AO<\/a>.<\/p>\n\n\n\n

Fertil Steril.<\/strong> 1999 Mar;71(3):425-30. Role of mutations Trp8\u21d2Arg and Ile15\u21d2Thr of the human luteinizing hormone beta-subunit in women with polycystiic ovary syndrome.<\/strong><\/a><\/p>\n\n\n\n

 Elter K, Erel CT, Cine N, Ozbek U, Hacihanefioglu B, Ertungealp E.<\/p>\n\n\n

<\/i><\/p>","protected":false},"excerpt":{"rendered":"

Op. Dr. Burak HACIHANEF\u0130O\u011eLU Dr. Burak Hac\u0131hanefio\u011flu 1969 y\u0131l\u0131nda \u0130stanbul\u2019da do\u011fdu. 1986 y\u0131l\u0131nda girdi\u011fi Hacettepe \u00dcniversitesi T\u0131p Fak\u00fcltesinden 1993 y\u0131l\u0131nda mezun oldu. 1993-1999 y\u0131llar\u0131 aras\u0131nda \u0130stanbul \u00dcniversitesi Cerrahpa\u015fa T\u0131p Fak\u00fcltesi\u2019nde Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum ihtisas\u0131 yapt\u0131. Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum ihtisas\u0131 d\u00f6neminde \u2018\u2019Polikistik Ovaryum Sendromunda \u0130ns\u00fclin Direnci ve Renin-Angiotensin sistemi (RAS) aras\u0131ndaki ili\u015fkinin de\u011ferlendirilmesi\u2019\u2019 konulu […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1892","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/1892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/comments?post=1892"}],"version-history":[{"count":23,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/1892\/revisions"}],"predecessor-version":[{"id":13035,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/1892\/revisions\/13035"}],"wp:attachment":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/media?parent=1892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}