{"id":7974,"date":"2025-09-27T19:47:35","date_gmt":"2025-09-27T19:47:35","guid":{"rendered":"https:\/\/polikistikover.net\/yeni\/?page_id=7974"},"modified":"2025-11-16T22:37:18","modified_gmt":"2025-11-16T22:37:18","slug":"polikistik-over-sendromunda-cinsel-istek-ve-escinsellik-lezbiyen-gay-transseksuel","status":"publish","type":"page","link":"https:\/\/polikistikover.net\/yeni\/polikistik-over-sendromunda-cinsel-istek-ve-escinsellik-lezbiyen-gay-transseksuel\/","title":{"rendered":"Polikistik Over Sendromu\u2019nda Cinsel \u0130stek ve E\u015fcinsellik (Lezbiyen, Gay, Transseks\u00fcel)"},"content":{"rendered":"\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Polikistik Over Sendromu\u2019nda cinsel iste\u011fi erkeklik hormonlar\u0131 (testosteron, dihidrotestosteron) ve \u00f6strojen (estradiol) hormonu belirlemektedir(5).<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Beyinde bulunan cinsel istek al\u0131c\u0131lar\u0131 (resept\u00f6r) testosteron taraf\u0131ndan uyar\u0131lmaktad\u0131r(6).<\/mark><\/strong><\/p>\n\n\n\n<p><strong><mark style=\"background-color:#08fd14\" class=\"has-inline-color\">1-<\/mark><\/strong>Polikistik Over Sendromu olan kad\u0131nlar\u0131n bir k\u0131sm\u0131nda erkeklik hormonlar\u0131 fazla miktarda \u00fcretilmektedir. Bir k\u0131sm\u0131nda ise erkeklik hormonu miktar\u0131 normal olmas\u0131na ra\u011fmen ba\u011flanarak onlar\u0131 etkisiz hale getiren madde olan&nbsp;Sex Hormone Binding Globulin (SHBG)&nbsp;daha az miktarda \u00fcretilmektedir.<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#47f709\" class=\"has-inline-color\">2-<\/mark><\/strong>SHBG miktar\u0131n\u0131n az olmas\u0131 erkeklik hormonu miktar\u0131n\u0131n normal seviyede olmas\u0131na ra\u011fmen serbest dola\u015fan yani ba\u011flanmam\u0131\u015f olan erkeklik hormonlar\u0131n\u0131n (serbest testosteron) miktar ve etkinli\u011finin artmas\u0131na neden olmaktad\u0131r(6,7).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#49f90b\" class=\"has-inline-color\">3-<\/mark><\/strong>SHBG ye ba\u011flanmam\u0131\u015f testosteron&nbsp;erkeklik hormonlar\u0131n\u0131n en etkili formu olan&nbsp;dihidrotestosteron&nbsp;(DHT) hormonuna d\u00f6n\u00fc\u015fmektedir.<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#08f813\" class=\"has-inline-color\">4-<\/mark><\/strong>Cinsel istek (cinsellik)&nbsp;erkeklik hormonlar\u0131 ve onlar\u0131n son \u00fcr\u00fcn\u00fc olan&nbsp;dihidrotestosteron&nbsp;miktar\u0131 ile do\u011fru orant\u0131l\u0131 olarak, SHBG miktar\u0131 ile ters orant\u0131l\u0131 olarak de\u011fi\u015fmektedir(10).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#0af815\" class=\"has-inline-color\">5-<\/mark><\/strong>Do\u011fum kontrol hap\u0131 kullanan ki\u015filerde&nbsp;yumurtal\u0131klar bask\u0131land\u0131\u011f\u0131 i\u00e7in erkeklik hormonu \u00fcretimi azal\u0131r ve SHBG miktar\u0131 artar. Bunun sonucunda do\u011fum kontrol hap\u0131 kullanan ki\u015filerde zaman i\u00e7inde cinsel isteksizlik ortaya \u00e7\u0131kabilmektedir(8,9).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#12f70d\" class=\"has-inline-color\">6-<\/mark><\/strong>Polikistik over sendromu olsun ya da olmas\u0131n b\u00fct\u00fcn kad\u0131nlarda erkeklik hormonlar\u0131n\u0131n miktarlar\u0131 ya\u015f ilerledik\u00e7e 20 li ya\u015flardan itibaren&nbsp;\u00f6zellikle 40 l\u0131 ya\u015flar\u0131 takiben azalmaktad\u0131r(35). Bunun sonucunda ya\u015f ilerledik\u00e7e zaman i\u00e7inde cinsel isteksizlik ortaya \u00e7\u0131kabilmektedir. Fakat, Polikistik over sendromu\u2019nda erkeklik hormonlar\u0131 polikistik over sendromu olmayan kad\u0131nlara g\u00f6re daha fazla miktarlarda olmaya ileri ya\u015flarda hatta&nbsp;menopoz&nbsp;sonras\u0131nda da devam etmektedir(36,37,38,39,40,41,42).<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Polikistik over sendromu olan kad\u0131nlar\u0131n bir k\u0131sm\u0131nda erkeklik hormonlar\u0131n\u0131n fazla miktarda \u00fcretilmesi ve fazla miktarda \u00fcretilen erkeklik hormonlar\u0131n\u0131n da daha fazla miktarda&nbsp;dihidrotestosteron&nbsp;hormonuna d\u00f6n\u00fc\u015fmesi nedeniyle cinsel istek (libido) art\u0131\u015f\u0131 ile birlikte&nbsp;agresif, sald\u0131rgan, gergin, sinirli ve \u00f6fkeli davran\u0131\u015flar\u0131&nbsp;i\u00e7eren&nbsp;psikolojik sorunlar&nbsp;g\u00f6r\u00fclebilmektedir(1,2,3).<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-blue-color\">Polikistik over sendromu olan kad\u0131nlardan erkeklik hormonlar\u0131 fazla miktarda \u00fcretilenlerde e\u015fcinsel (lezbiyen,&nbsp;gay) olma ihtimalinin polikistik over sendromu olmayan kad\u0131nlardan daha fazla oldu\u011fu g\u00f6r\u00fclmektedir(43,44,45,46).<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Polikistik over sendromu olan e\u015fcinsel kad\u0131nlar\u0131n bir k\u0131sm\u0131nda daha \u00e7ok k\u0131sa sa\u00e7, erkeksi giyim ve davran\u0131\u015flar\u0131 i\u00e7eren erkek rol\u00fcn\u00fcn (butch) \u00fcstlenildi\u011fi g\u00f6r\u00fclmektedir.<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">&nbsp;Kad\u0131ndan erke\u011fe cinsiyet de\u011fi\u015fikli\u011fi (female-to-male transsexulas)&nbsp;g\u00f6sterenlerin b\u00fcy\u00fck bir k\u0131sm\u0131nda da erke\u011fe d\u00f6n\u00fc\u015f\u00fcm amac\u0131yla herhangi bir erkeklik hormonu tedavisi kullanmadan, yine erke\u011fe d\u00f6n\u00fc\u015f\u00fcm amac\u0131yla yumurtal\u0131klar (oophorectomy) ve memeler (mastectomy) ameliyat ile \u00e7\u0131kart\u0131lmadan \u00f6nce erkeklik hormonlar\u0131 fazla miktarda \u00fcretilmektedir(43,44,45).<\/mark><\/strong><\/p>\n\n\n\n<p>Polikistik over sendromu olan normal kilolu veya zay\u0131f ya da fazla kilolu veya&nbsp;\u015fi\u015fman e\u015fcinsel kad\u0131nlar\u0131n bir k\u0131sm\u0131nda kar\u0131n ve bel \u00e7evresinde&nbsp;ya\u011f miktar\u0131 fazla&nbsp;(erkek tipi ya\u011flanma)&nbsp;oldu\u011fu i\u00e7in bel \u00e7evresi&nbsp;kal\u0131nl\u0131\u011f\u0131 g\u00f6r\u00fclmektedir(47,48,49,50,51). <\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Polikistik over sendromu olan ve bel \u00e7evresi kal\u0131n kad\u0131nlarda bel \u00e7evresi kal\u0131n olmayan ayn\u0131 kiloya sahip kad\u0131nlara g\u00f6re daha&nbsp;fazla oranda kalp ve damar hastal\u0131\u011f\u0131 ihtimalini artt\u0131ran&nbsp;metabolik sendrom&nbsp;ortaya \u00e7\u0131kmaktad\u0131r(52,53).<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Polikistik over sendromu\u2019nda fazla kilolu ve \u015fi\u015fman olan veya normal kilolu fakat bel \u00e7evresi kal\u0131n&nbsp;(erkek tipi ya\u011flanma)&nbsp;olan e\u015fcinsel kad\u0131nlar\u0131n b\u00fcy\u00fck \u00e7o\u011funlu\u011funda&nbsp;ins\u00fclin direnci&nbsp;g\u00f6r\u00fclmektedir(45,46).<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">\u0130ns\u00fclin direncinin ilerlemesi, k\u00f6t\u00fcye gitmesi sonucunda bu kad\u0131nlarda&nbsp;bozulmu\u015f glukoz (\u015feker) tolerans\u0131 ve \u015feker hastal\u0131\u011f\u0131 (Diabetes mellitus)&nbsp;geli\u015fmektedir(54,55,56,57,58,59,60).<\/mark><\/strong><\/p>\n\n\n\n<p><strong><mark style=\"background-color:#fb0707\" class=\"has-inline-color\">1-<\/mark><\/strong>Erkeklik hormonlar\u0131n\u0131n (testosteron, dihidrotestosteron) b\u00fcy\u00fck bir k\u0131sm\u0131 b\u00f6brek \u00fcst\u00fc bezinde (Adrenal Gland) \u00fcretilen DHEA (Dehydroepiandrosterone) ve Androstenedione hormonlar\u0131n\u0131 hammadde olarak kullanarak k\u0131l k\u00f6kleri ve ya\u011f bezlerinin bulundu\u011fu deri, ya\u011f dokusu ve meme gibi ayn\u0131 zamanda erkeklik hormonlar\u0131n\u0131n (testosteron, dihidrotestosteron) hedefi olan organlarda\u00a0\u00fcretilirken ancak k\u00fc\u00e7\u00fck bir k\u0131sm\u0131 yumurtal\u0131k ve b\u00f6brek \u00fcst\u00fc bezinde \u00fcretilmektedir\u00a0(Intracrinology)(11,12).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#f90a0a\" class=\"has-inline-color has-dark-color\">2-<\/mark><\/strong>Kan dola\u015f\u0131m\u0131nda bulunan testosteron miktar\u0131 sadece yumurtal\u0131k ve b\u00f6brek \u00fcst\u00fc bezinden do\u011frudan sal\u0131nan miktar\u0131 g\u00f6stermektedir.<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#f71108\" class=\"has-inline-color\">3-<\/mark><\/strong>Kad\u0131nlarda testosteron hormonunun b\u00fcy\u00fck k\u0131sm\u0131n\u0131n\u00a0\u00fcretildi\u011fi deri, ya\u011f dokusu, meme gibi organlardan ancak k\u00fc\u00e7\u00fck bir miktar (%10) testosteron kan dola\u015f\u0131m\u0131na girmektedir(13).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#fb0b0b\" class=\"has-inline-color\">4-<\/mark><\/strong>Kan dola\u015f\u0131m\u0131na girmeyen testosteron hormonunun b\u00fcy\u00fck \u00e7o\u011funlu\u011fu ise 5-\u00a0\u03b1 reduktaz (reductase) enzimi taraf\u0131ndan dihidrotestosteron (dhydrotestosterone) hormonuna d\u00f6n\u00fc\u015fmektedir(14,15,16).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#fe0b0b\" class=\"has-inline-color\">5-<\/mark><\/strong>Dihidrotestosteron hormonu testosteron hormonundan 10 kat daha g\u00fc\u00e7l\u00fc bir etkiye sahiptir(17).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#f90808\" class=\"has-inline-color\">6-<\/mark><\/strong>Dihidrotestosteron hormonunun da testosteron hormonu gibi b\u00fcy\u00fck \u00e7o\u011funlu\u011fu (%90) kan dola\u015f\u0131m\u0131na girmemektedir(15,18).\u00a0<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#f90e0e\" class=\"has-inline-color\">7-<\/mark><\/strong>Deri, ya\u011f dokusu, meme gibi organlarda \u00fcretilen\u00a0dihidrotestosteron (DHT)\u00a0hormonunun b\u00fcy\u00fck \u00e7o\u011funlu\u011fu UGT- enzimi ile herhangi bir hormon etkisi olmayan \u00fcr\u00fcnler\u00a0(metabolit) olan 3\u00a0\u03b1- androstanediol glucuronide (3\u03b1 diol G) ve androsterone Glucuronide (ADT-G) d\u00f6n\u00fc\u015ferek deri h\u00fccresinden kan dola\u015f\u0131m\u0131na girmektedir(19,20,21,22).<\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong>Tedavi;<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-dark-pink-color\">Dihidrotestosteron&nbsp;hormonunun hammaddesi olan erkeklik hormonlar\u0131n\u0131n etkinli\u011finin ve miktar\u0131n\u0131n azalt\u0131lmas\u0131,&nbsp;dihidrotestosteron&nbsp;hormonuna d\u00f6n\u00fc\u015f\u00fcm\u00fcn azalt\u0131lmas\u0131 ve&nbsp;Sex Hormon Binding Globulin&nbsp;miktar\u0131n\u0131n artt\u0131r\u0131lmas\u0131 sonucunda cinsel istek (libido) art\u0131\u015f\u0131 ile birlikte&nbsp;agresif, sald\u0131rgan, gergin, sinirli ve \u00f6fkeli davran\u0131\u015flar\u0131 i\u00e7eren&nbsp;psikolojik sorunlar&nbsp;d\u00fczelebilmektedir.&nbsp;<\/mark><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong>Tedavi Y\u00f6ntemleri;<\/strong><\/p>\n\n\n\n<p><strong><mark style=\"background-color:#08c4f4\" class=\"has-inline-color\">1-<\/mark><\/strong> \u0130ns\u00fclin direnci&nbsp;olan kad\u0131nlarda ins\u00fclin duyarl\u0131l\u0131\u011f\u0131n\u0131n ila\u00e7 tedavisi ile artt\u0131r\u0131lmas\u0131na ba\u011fl\u0131 olarak kan dola\u015f\u0131m\u0131nda bulunan ins\u00fclin miktar\u0131n\u0131n azalmas\u0131 yumurtal\u0131kta fazla miktarda \u00fcretilen erkeklik hormonlar\u0131n\u0131 (androstenedione, testosteron) azaltmaktad\u0131r(23,24). \u0130ns\u00fclin direncinin azalmas\u0131 ayn\u0131 zamanda karaci\u011ferde \u00fcretilen SHBG miktar\u0131n\u0131 artt\u0131rmakta ve erkeklik hormonlar\u0131n\u0131n serbest dola\u015fan etkin formlar\u0131n\u0131n (serbest testosteron) miktar\u0131n\u0131n azalmas\u0131na neden olmaktad\u0131r(23,24).<\/p>\n\n\n\n<p><mark style=\"background-color:#0896f9\" class=\"has-inline-color\">2-<\/mark> Kan dola\u015f\u0131m\u0131nda bulunan erkeklik hormonlar\u0131n\u0131n bir k\u0131sm\u0131&nbsp;al\u0131c\u0131lara (androgen receptor)&nbsp;tutunarak etki etmektedir. Erkeklik hormonlar\u0131n\u0131n al\u0131c\u0131lara tutunmas\u0131n\u0131n engellenmesi (androgen receptor antagonist) di\u011fer&nbsp;bir tedavi se\u00e7ene\u011fidir(4,25,26,27).&nbsp;Bu ama\u00e7la&nbsp;kullan\u0131lan ila\u00e7lar\u0131n (androgen receptor antagonist) do\u011fum kontrol haplar\u0131 gibi hayati tehlikeye sahip yan etkileri (bacak damarlar\u0131n\u0131n p\u0131ht\u0131 ile t\u0131kanmas\u0131&nbsp;ve ordan kopan p\u0131ht\u0131 par\u00e7as\u0131n\u0131n da akci\u011fer damarlar\u0131n\u0131 t\u0131kamas\u0131 ve meme kanseri) yoktur(28,29,30).<\/p>\n\n\n\n<p><mark style=\"background-color:#0578f1\" class=\"has-inline-color\">3-<\/mark> Al\u0131c\u0131lara (receptor) tutunarak h\u00fccre i\u00e7ine giren testosteron ile h\u00fccrede \u00fcretilen testosteron hormonunun b\u00fcy\u00fck \u00e7o\u011funlu\u011fu 5-&nbsp;\u03b1 reduktaz (reductase) enzimi taraf\u0131ndan dihidrotestosteron (dhydrotestosterone) hormonuna d\u00f6n\u00fc\u015fmektedir(14,15,16).<\/p>\n\n\n\n<p>&nbsp;5-&nbsp;\u03b1 reduktaz (reductase) enziminin bu etkisinin engellenmesi (5-&nbsp;\u03b1 &nbsp;reductase inhibitor) de bir tedavi se\u00e7ene\u011fidir(31,32,33).&nbsp;Bu ama\u00e7la&nbsp;kullan\u0131lan ila\u00e7lar\u0131n (5-\u03b1 reductase inhibitor) do\u011fum kontrol haplar\u0131 gibi hayati tehlikeye sahip yan etkileri (bacak damarlar\u0131n\u0131n p\u0131ht\u0131 ile t\u0131kanmas\u0131&nbsp;ve ordan kopan p\u0131ht\u0131 par\u00e7as\u0131n\u0131n da akci\u011fer damarlar\u0131n\u0131 t\u0131kamas\u0131 ve meme kanseri) yoktur(34).<\/p>\n\n\n\n<p><strong><mark style=\"background-color:#0571f4\" class=\"has-inline-color\">4-<\/mark><\/strong> Polikistik over sendromu olan kad\u0131nlarda&nbsp;ya\u015fanan&nbsp;psikolojik sorunlar\u0131n&nbsp;\u00e7\u00f6z\u00fcmlenmesine y\u00f6nelik al\u0131nacak profesyonel bir psikiyatrik yard\u0131m ve polikistik over Sendromu\u2019nun tedavisi birlikte bir b\u00fct\u00fcnl\u00fck olu\u015fturmaktad\u0131r.<\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong>Kaynaklar<\/strong><\/p>\n\n\n\n<p>1-Risk of psychiatric disorders following polycystic ovary syndrome: a nationwide population-based cohort study. Hung JH, Hu LY, Tsai SJ, Yang AC, Huang MW, Chen PM, Wang SL, Lu T, Shen CC.&nbsp;PLoS One. 2014&nbsp;May 9;9(5):e97041.<\/p>\n\n\n\n<p>2-Androgens and mood dysfunction in women: comparison of women with polycystic ovarian syndrome to healthy controls. Weiner CL, Primeau M, Ehrmann DA.&nbsp;Psychosom Med. 2004 May-Jun;66(3):356-62.<\/p>\n\n\n\n<p>3-Psychological parameters in the reproductive phenotypes of polycystic ovary syndrome. Moran LJ, Deeks AA, Gibson-Helm ME, Teede HJ.&nbsp;Hum Reprod. 2012 Jul;27(7):2082-8.<\/p>\n\n\n\n<p>4-The role&nbsp;of androgen receptor&nbsp;in skin related disorders. Lai JJ, Chang P, Lai KP, Chen L, Chang C. Arch Dermatol Res. 2012 Sep;304(7):499-510.<\/p>\n\n\n\n<p>5-Neurosteroids: a novel function of the brain.&nbsp;Baulieu EE&nbsp;Psychoneuroendocrinology. 1998&nbsp;&nbsp;Nov;23(8):963-87.<\/p>\n\n\n\n<p>6-Hormone receptors&nbsp;and sexuality in the human female.&nbsp;DeCherney AH.&nbsp;J Womens Health Gend Based Med. 2000;9 Suppl 1:S9-13.<\/p>\n\n\n\n<p>7-Implications of hormonal influences on sexual behavior for demographic models of reproduction.&nbsp;Campbell BC, Udry JR.&nbsp;Ann N Y Acad Sci. 1994 Feb 18;709:117-27.<\/p>\n\n\n\n<p>8-Hormonal contraception and sexual desire: A questionnaire-based study of young Swedish women.&nbsp;Malmborg A, Persson E, Brynhildsen J, Hammar M.&nbsp;Eur J Contracept Reprod Health Care. 2016;21(2):158-67.<\/p>\n\n\n\n<p>9-Oral contraceptives, androgens, and the sexuality of young women: II. The role of androgens.&nbsp;Bancroft J&nbsp;, Sherwin BB, Alexander GM, Davidson DW, Walker A.&nbsp;Arch Sex Behav. 1991&nbsp;&nbsp;Apr;20(2):121-35.<\/p>\n\n\n\n<p>10-Controlled studies on women presenting with sexual drive disorder: I. Endocrine status.&nbsp;Riley A, Riley E.&nbsp;J Sex&nbsp;Marital Ther. 2000 Jul-Sep;26(3):269-83.<\/p>\n\n\n\n<p>11-Intracrinology. Labrie F.&nbsp;Mol Cell Endocrinol. 1991&nbsp;Jul;78(3):C113-8.<\/p>\n\n\n\n<p>12-Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Labrie F, Luu-The V, Labrie C, B\u00e9langer A, Simard J, Lin SX, Pelletier G.&nbsp;Endocr Rev. 2003&nbsp;Apr;24(2):152-82.<\/p>\n\n\n\n<p>13-DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. 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Beyinde bulunan cinsel istek al\u0131c\u0131lar\u0131 (resept\u00f6r) testosteron taraf\u0131ndan uyar\u0131lmaktad\u0131r(6). 1-Polikistik Over Sendromu olan kad\u0131nlar\u0131n bir k\u0131sm\u0131nda erkeklik hormonlar\u0131 fazla miktarda \u00fcretilmektedir. Bir k\u0131sm\u0131nda ise erkeklik hormonu miktar\u0131 normal olmas\u0131na ra\u011fmen ba\u011flanarak onlar\u0131 etkisiz hale getiren madde olan&nbsp;Sex Hormone Binding Globulin (SHBG)&nbsp;daha [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7974","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/7974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/comments?post=7974"}],"version-history":[{"count":20,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/7974\/revisions"}],"predecessor-version":[{"id":11184,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/7974\/revisions\/11184"}],"wp:attachment":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/media?parent=7974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}