{"id":8419,"date":"2025-09-28T10:50:00","date_gmt":"2025-09-28T10:50:00","guid":{"rendered":"https:\/\/polikistikover.net\/yeni\/?page_id=8419"},"modified":"2025-11-23T20:32:15","modified_gmt":"2025-11-23T20:32:15","slug":"meme-kanseri-ve-insulin-direnci","status":"publish","type":"page","link":"https:\/\/polikistikover.net\/yeni\/meme-kanseri-ve-insulin-direnci\/","title":{"rendered":"Meme Kanseri ve \u0130ns\u00fclin Direnci"},"content":{"rendered":"\n

1-<\/mark><\/strong>\u0130ns\u00fclin direnci ve onu takiben geli\u015fen \u015feker hastal\u0131\u011f\u0131 meme kanseri g\u00f6r\u00fclme ihtimalini artt\u0131rmaktad\u0131r(1,2,3,4). <\/p>\n\n\n\n

2-<\/mark><\/strong>\u0130ns\u00fclin direnci ve ins\u00fclin direncine kar\u015f\u0131 fazla miktarda \u00fcretilen ins\u00fclin hormonu (hiperins\u00fclinemi) \u015fi\u015fmanl\u0131ktan ba\u011f\u0131ms\u0131z olarak yani ins\u00fclin direnci olan zay\u0131f kad\u0131nlarda da meme kanseri ihtimalini artt\u0131rmaktad\u0131r(1,4).<\/p>\n\n\n\n

3-<\/mark><\/strong>Meme kanseri olu\u015fan b\u00f6lgede fazla say\u0131da ins\u00fclin hormonuna ba\u011flanan al\u0131c\u0131lar (resept\u00f6rler) bulunmaktad\u0131r(2).<\/p>\n\n\n\n

4-<\/mark><\/strong>Bu al\u0131c\u0131lara tutunan fazla miktarda \u00fcretilen ins\u00fclin hormonu meme kanserinin b\u00fcy\u00fcmesine neden olmaktad\u0131r. <\/p>\n\n\n\n

5-<\/mark><\/strong>ins\u00fclin direncine ba\u011fl\u0131 olarak fazla miktarda \u00fcretilen ins\u00fclin hormonu sex hormon binding globulin miktar\u0131n\u0131 azaltarak kanda serbest dola\u015fan \u00f6strojen miktar\u0131n\u0131 artt\u0131rmaktad\u0131r. <\/p>\n\n\n\n

6-<\/mark><\/strong>Serbest dola\u015fan \u00f6strojen miktar\u0131n\u0131n fazla olmas\u0131 meme kanseri ihtimalini artt\u0131ran ba\u015fka bir durumdur.<\/p>\n\n\n\n

Polikistik over sendromu olan kad\u0131nlar\u0131n yakla\u015f\u0131k yar\u0131s\u0131nda \u0130ns\u00fclin direnci ve\u00a0onu takiben geli\u015fen \u015feker hastal\u0131\u011f\u0131 ins\u00fclin direnci vard\u0131r.\u00a0<\/mark><\/strong><\/p>\n\n\n\n

Protein miktar\u0131 d\u00fc\u015f\u00fck buna kar\u015f\u0131l\u0131k karbonhidrat miktar\u0131 fazla olan yani glisemik indeksi y\u00fcksek beslenme bi\u00e7imi ve hareketsiz bir ya\u015fam s\u00fcr\u00fclmesi polikistik over sendromu olan kad\u0131nlarda meme kanseri ihtimalini artt\u0131ran durumlardan biri olan ins\u00fclin direncinin ortaya \u00e7\u0131kmas\u0131n\u0131 kolayla\u015ft\u0131rmaktad\u0131r(5).<\/mark><\/strong><\/p>\n\n\n\n

Kaynaklar<\/strong><\/p>\n\n\n\n

1-Insulin resistance and breast-cancer risk. Bruning PF, Bonfr\u00e8r JM, van Noord PA, Hart AA, de Jong-Bakker M, Nooijen WJ. Int J Cancer. 1992 Oct 21;52(4):511-6.<\/p>\n\n\n\n

2-Elevated insulin receptor content in human breast cancer. Papa V, Pezzino V, Costantino A, Belfiore A, Giuffrida D, Frittitta L, Vannelli GB, Brand R, Goldfine ID, Vigneri R. J Clin Invest. 1990 Nov;86(5):1503-10.<\/p>\n\n\n\n

3-Association between insulin resistance and breast carcinoma: a systematic review and meta-analysis. Hernandez AV, Guarnizo M, Miranda Y, Pasupuleti V, Deshpande A, Paico S, Lenti H, Ganoza S, Montalvo L, Thota P,Lazaro H. PLoS One. 2014 Jun 9;9(6):e99317.<\/p>\n\n\n\n

4-Selected medical conditions and risk of breast cancer. Talamini R, Franceschi S, Favero A, Negri E, Parazzini F, La Vecchia C. Br J Cancer. 1997;75(11):1699-703.<\/p>\n\n\n\n

5-Intake of macronutrients and risk of breast cancer. Franceschi S, Favero A, Decarli A, Negri E, La Vecchia C, Ferraroni M, Russo A, Salvini S, Amadori D, Conti E, Montella M, Giacosa A. Lancet. 1996 May 18;347(9012):1351-6.<\/p>\n","protected":false},"excerpt":{"rendered":"

1-\u0130ns\u00fclin direnci ve onu takiben geli\u015fen \u015feker hastal\u0131\u011f\u0131 meme kanseri g\u00f6r\u00fclme ihtimalini artt\u0131rmaktad\u0131r(1,2,3,4). 2-\u0130ns\u00fclin direnci ve ins\u00fclin direncine kar\u015f\u0131 fazla miktarda \u00fcretilen ins\u00fclin hormonu (hiperins\u00fclinemi) \u015fi\u015fmanl\u0131ktan ba\u011f\u0131ms\u0131z olarak yani ins\u00fclin direnci olan zay\u0131f kad\u0131nlarda da meme kanseri ihtimalini artt\u0131rmaktad\u0131r(1,4). 3-Meme kanseri olu\u015fan b\u00f6lgede fazla say\u0131da ins\u00fclin hormonuna ba\u011flanan al\u0131c\u0131lar (resept\u00f6rler) bulunmaktad\u0131r(2). 4-Bu al\u0131c\u0131lara tutunan fazla miktarda \u00fcretilen ins\u00fclin hormonu […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8419","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/8419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/comments?post=8419"}],"version-history":[{"count":8,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/8419\/revisions"}],"predecessor-version":[{"id":11662,"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/pages\/8419\/revisions\/11662"}],"wp:attachment":[{"href":"https:\/\/polikistikover.net\/yeni\/wp-json\/wp\/v2\/media?parent=8419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}