Polikistik Over
Dr. Burak Hacıhanefioğlu
polikistikover.net internet sitesinde yer alan tıp içerikli yazı ve videoların tümü Kadın Hastalıkları ve Doğum Uzmanı Dr. Burak Hacıhanefioğlu tarafından hazırlanmış olup, telif hakları yasal koruma altına alınmıştır. İzinsiz kaynak gösterilerek dahi başka bir yerde yayınlanamaz.
Polikistik over sendromu’nda fazla kilolu veya şişman ya da normal kilolu, hatta zayıf, fakat karın ve bel çevresinde yağ miktarı fazla (erkek tipi yağlanma) olan kadınlarda insülin direnci görülmektedir(1,2,3,4). Sigarada bulunan nikotin de insülin direncine neden olmaktadır. (5,6,7,8,9,10). Sigaranın kilo almayı önleyici etkisi nedeniyle fazla kilolu olmayan bu kadınların bel ve karın bölgesinde insülin direncinin belirtisi olan erkek tipi yağlanma artışı görülmektedir(11). Sigara kullanan polikistik over sendromu olan kadınlarda kilo artışı olmasa bile karın ve bel çevresinde yağ miktarı fazlalığı ve insülin direnci artmaktadır(11,12,13,14,15).
Polikistik over sendromu olan ve sigara içen kadınlarda sigarada bulunan nikotin, erkeklik hormonlarının (testosteron) etkisiz maddelere (metabolit) dönüşerek vücuttan atılmasını engellemektedir(16,17). Bu nedenle sigara kullanan polikistik over sendromu olan kadınlarda testosteron miktarı daha da artmaktadır(18,19,20).
KAYNAKLAR
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